Which sign is commonly associated with Graves' disease?

Which sign is commonly associated with Graves' disease?

• A. Moon face
• B. Buffalo hump
• C. Exophthalmos
• D. Apathy

Answer: (C)

Graves' disease often presents with ocular symptoms, most characteristically exophthalmos. This occurs because autoimmune activity targets tissues behind the eyes, causing inflammation and accumulation of connective tissue and fluid in the orbital space. The result is forward displacement of the eyes, sometimes with eyelid retraction and diplopia. Moon face and buffalo hump point to Cushing syndrome, not Graves', while apathy isn’t a hallmark sign of thyrotoxicosis. So the sign you’d most expect with Graves' disease is exophthalmos.

Graves' disease often presents with ocular symptoms, most characteristically exophthalmos. This occurs because autoimmune activity targets tissues behind the eyes, causing inflammation and accumulation of connective tissue and fluid in the orbital space. The result is forward displacement of the eyes, sometimes with eyelid retraction and diplopia. Moon face and buffalo hump point to Cushing syndrome, not Graves', while apathy isn’t a hallmark sign of thyrotoxicosis. So the sign you’d most expect with Graves' disease is exophthalmos.